技術規格
Background: |
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. |
Applications: |
ELISA, IHC |
Name of antibody: |
ITGAE |
Immunogen: |
Fusion protein of human ITGAE |
Full name: |
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) |
Synonyms: |
CD103; HUMINAE |
SwissProt: |
P38570 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human colon cancer and Human lung cancer |
IHC Recommend dilution: |
50-200 |