Background: |
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. |
Applications: |
ELISA, IHC |
Name of antibody: |
IRAK3 |
Immunogen: |
Fusion protein of human IRAK3 |
Full name: |
interleukin-1 receptor-associated kinase 3 |
Synonyms: |
ASRT5; IRAKM |
SwissProt: |
Q9Y616 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human thyroid cancer |
IHC Recommend dilution: |
25-100 |