中文名稱:CASP2抗原(重組蛋白)
英文名稱:CASP2 Antigen (Recombinant Protein)
儲 存:冷凍(-20℃)
相關類別:抗原
概述
Fusion protein corresponding to N terminal 201 amino acids of human CASP2 |
技術規格
Full name: |
Caspase-2 |
Synonyms: |
ICH1, NEDD2, CASP-2, NEDD-2 |
Swissprot: |
P42575 |
Gene Accession: |
BC002427 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |