抗 原: INS(C-peptide)
技術規(guī)格
Background: |
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. |
Applications: |
ELISA, IHC |
Name of antibody: |
INS(C-peptide) |
Immunogen: |
Synthetic peptide of human INS(C-peptide) |
Full name: |
insulin |
Synonyms: |
IDDM; ILPR; IRDN; IDDM1; IDDM2; MODY10 |
SwissProt: |
P01308 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human tonsil and Human liver cancer |
IHC Recommend dilution: |
25-50 |