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021-54845833/15800441009
中文名稱： 兔抗IL21R多克隆抗體
英文名稱： Anti-IL21R rabbit polyclonal antibody
儲 存： 冷凍（-20℃）
抗 原： IL21R
相關(guān)類別： 一抗
反應種屬： Human
標 記 物： Unconjugate
Background:
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.
Applications:
ELISA, IHC
Name of antibody:
IL21R
Immunogen:
Fusion protein of human IL21R
Full name:
interleukin 21 receptorp
Synonyms：
NILR; CD360
SwissProt:
Q9HBE5
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human thyroid cancer and human lung cancer
IHC Recommend dilution:
25-100
技術(shù)規(guī)格
