中文名稱:APP抗原(重組蛋白)
英文名稱:APP Antigen (Recombinant Protein)
儲 存:冷凍(-20℃)
相關類別:抗原
概述
Fusion protein corresponding to N terminal 304 amino acids of human APP |
技術規格
Full name: |
amyloid beta (A4) precursor protein |
Synonyms: |
AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma |
Swissprot: |
P05067 |
Gene Accession: |
BC004369 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. |