中文名稱:APLP1抗原(重組蛋白)
英文名稱:APLP1 Antigen (Recombinant Protein)
儲 存:冷凍(-20℃)
相關類別:抗原
概述
Fusion protein corresponding to a region derived from 56-342 of human APLP1 |
技術規(guī)格
Full name: |
Amyloid beta (A4) precursor-like protein 1 |
Synonyms: |
APLP |
Swissprot: |
P51693 |
Gene Accession: |
BC012889 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. |