技術規格
Background:
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.
Applications:
ELISA, WB, IHC
Name of antibody:
IL7
Immunogen:
Synthetic peptide of human IL7
Full name:
interleukin 7
Synonyms:
IL-7
SwissProt:
P13232
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human ovarian cancer and Human thyroid cancer
IHC Recommend dilution:
30-150
WB Predicted band size:
20 kDa
WB Positive control:
Human kidney tissue and Mouse kidney tissue lysates
WB Recommended dilution:
200-1000