中文名稱:ALOX15B抗原(重組蛋白)
英文名稱:ALOX15B Antigen (Recombinant Protein)
儲 存:冷凍(-20℃)
相關(guān)類別:抗原
概述
Fusion protein corresponding to a region derived from 30-351 amino acids of human ALOX15B
技術(shù)規(guī)格
Full name:
arachidonate 15-lipoxygenase, type B
Synonyms:
15-LOX-2
Swissprot:
O15296
Gene Accession:
BC063647
Purity:
>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:
Escherichia coli
Tags:
His tag C-Terminus, GST tag N-Terminus
Background:
This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described.