抗 原: IDH3B
儲 存: 冷凍(-20℃)
宿 主: Rabbit
克隆類型: rabbit polyclonal
技術規格
Background: |
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
IDH3B |
Immunogen: |
Fusion protein of human IDH3B |
Full name: |
isocitrate dehydrogenase 3 (NAD+) beta |
Synonyms: |
RP46; H-IDHB |
SwissProt: |
O43837 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human thyroid cancer |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
42 kDa |
WB Positive control: |
HepG2 cells and mouse kidney tissue, lovo cells and mouse eyes tissue, hela cells |
WB Recommended dilution: |
200-1000 |