購物車
幫助
021-54845833/15800441009
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Background: |
FXN, also named as FRDA, X25, m81-FXN, d-FXN, m78-FXN and i-FXN, belongs to the frataxin family. It promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. FXN may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. FXN is cleaved to be 4 chains. The mature form of FXN is 14kd or 18kd. |
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Applications: |
WB |
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Name of antibody: |
FXN |
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Immunogen: |
Fusion protein of human FXN |
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Full name: |
frataxin |
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Synonyms： |
CyaY; FA; FARR; FRDA; MGC57199; X25 |
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SwissProt: |
Q16595 |
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WB Predicted band size: |
23 kDa |
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WB Positive control: |
MDA-MB-453s cells |
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WB Recommended dilution: |
500-2000 |
