宿 主: Rabbit
抗 原: HDAC3
反應種屬: Human, Mouse, Rat
標 記 物: Unconjugate
技術規格
Background: |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. |
Applications: |
ELISA, WB |
Name of antibody: |
HDAC3 |
Immunogen: |
Synthetic peptide of human HDAC3 |
Full name: |
histone deacetylase 3 |
Synonyms: |
HD3; RPD3; RPD3-2 |
SwissProt: |
O15379 |
ELISA Recommended dilution: |
1000-2000 |
WB Predicted band size: |
49 kDa |
WB Positive control: |
A549, NIH/3T3, Raji, 293T and Hela cells |
WB Recommended dilution: |
200-1000 |