中文名稱:小鼠抗NDUFB9單克隆抗體
Background: |
The protein encoded by this gene is a subunit of the mitochondrial oxidative phosphorylation complex I (nicotinamide adenine dinucleotide: ubiquinone oxidoreductase). Complex I is localized to the inner mitochondrial membrane and functions to dehydrogenate nicotinamide adenine dinucleotide and to shuttle electrons to coenzyme Q. Complex I deficiency is the most common defect found in oxidative phosphorylation disorders and results in a range of conditions, including lethal neonatal disease, hypertrophic cardiomyopathy, liver disease, and adult-onset neurodegenerative disorders. Pseudogenes of this gene are found on chromosomes five, seven and eight. Alternative splicing results in multiple transcript variants. |
Applications: |
WB, IHC, FC |
Name of antibody: |
NDUFB9 |
Immunogen: |
Fusion protein of human NDUFB9 |
Full name: |
NADH:ubiquinone oxidoreductase subunit B9 (NDUFB9), transcript variant 1 |
Synonyms: |
B22; CI-B22; LYRM3; UQOR22 |
SwissProt: |
Q9Y6M9 |
IHC positive control: |
human kidney tissue and carcinoma of human liver tissue |
IHC Recommend dilution: |
30-150 |
WB Predicted band size: |
22 kDa |
WB Positive control: |
HepG2, Hela, A549, COS7, Jurkat, MCF-7 cell lysates |
WB Recommended dilution: |
500-2000 |