中文名稱:小鼠抗HDAC6單克隆抗體
技術規格
Background: |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. |
Applications: |
WB |
Name of antibody: |
HDAC6 |
Immunogen: |
Fusion protein of human HDAC6 |
Full name: |
histone deacetylase 6 |
Synonyms: |
HD6; JM21; CPBHM; PPP1R90 |
SwissProt: |
Q9UBN7 |
WB Predicted band size: |
131 kDa |
WB Positive control: |
T47D cell, Jurkat cell, CHO-K1 cell and CHO-K1 transfected by HDAC6-fragment EGFP fusion protein cell lysates |
WB Recommended dilution: |
1000-5000 |