中文名稱:小鼠抗GAD2單克隆抗體
Background: |
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. |
Applications: |
WB |
Name of antibody: |
GAD2 |
Immunogen: |
Fusion protein of human GAD2 |
Full name: |
glutamate decarboxylase 2 |
Synonyms: |
GAD65 |
SwissProt: |
Q05329 |
WB Predicted band size: |
65 kDa |
WB Positive control: |
Rat Hippocampus and Rat Brain tissue lysates |
WB Recommended dilution: |
1000-5000 |