中文名稱(chēng) : 小鼠抗DOK7單克隆抗體
Background: |
The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. [provided by RefSeq]. |
Applications: |
WB, IF, FC |
Name of antibody: |
DOK7 |
Immunogen: |
Fusion protein of human DOK7 |
Full name: |
docking protein 7 (DOK7), transcript variant 1 |
Synonyms: |
CMS10; CMS1B; C4orf25 |
SwissProt: |
Q18PE1 |
WB Predicted band size: |
53 kDa |
WB Positive control: |
SVT2 cell lysate |
WB Recommended dilution: |
200-1000 |