Name: ZUP1 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： ZUP1 抗原（重組蛋白）

英文名稱： ZUP1 Antigen (Recombinant Protein)

別名： zinc finger containing ubiquitin peptidase 1; DUB; ZUFSP; C6orf113

相關類別：抗原

儲存：冷凍（-20℃）

概述

Fusion protein corresponding to a region derived from 379-578 amino acids of human ZUP1

技術規格

Full name:	zinc finger containing ubiquitin peptidase 1
Synonyms:	DUB; ZUFSP; C6orf113
Swissprot:	Q96AP4
Gene Accession:	BC016879
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a protein containing zinc finger motifs and a cysteine peptidase domain. The encoded protein functions as a K63-specific de-ubiquitinating enzyme that specifically cleaves long K63-linked polyubiquitin chains in the middle of a chain (i.e. "endo cleavage) rather than by removing the terminal ubiquitin from a chain. This enzyme is thought to be involved in the regulation of DNA repair by cleaving K63-linked ubiquitin chains at repair foci. This protein is related to proteases for the ubiquitin-like modifiers Ufm1 (ubiquitin fold modifier 1) and Atg8/Gabarapl2, but does not have any activity on these modifiers. [provided by RefSeq, Mar 2018]

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