中文名稱:小鼠抗CTSD單克隆抗體
Background: |
This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. |
Applications: |
ELISA, WB |
Name of antibody: |
CTSD |
Immunogen: |
Fusion protein of human CTSD |
Full name: |
cathepsin D |
Synonyms: |
CPSD; CLN10; HEL-S-130P |
SwissProt: |
P07339 |
WB Predicted band size: |
45 kDa |
WB Positive control: |
MCF-7 whole cell lysate |
WB Recommended dilution: |
1000-5000 |