中文名稱:小鼠抗CFL1單克隆抗體
Background: |
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. |
Applications: |
ELISA, WB |
Name of antibody: |
CFL1 |
Immunogen: |
Fusion protein of human CFL1 |
Full name: |
cofilin 1 |
Synonyms: |
CFL; cofilin; HEL-S-15 |
SwissProt: |
P23528 |
WB Predicted band size: |
19 kDa |
WB Positive control: |
BGC823 whole cell lysate |
WB Recommended dilution: |
1000-5000 |