Name: UMPS 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： UMPS 抗原（重組蛋白）

英文名稱： UMPS Antigen (Recombinant Protein)

別名： uridine monophosphate synthetase; OPRT

相關類別：抗原

儲存： 冷凍（-20℃）

概述

Fusion protein corresponding to a region derived from 281-480 amino acids of human UMPS

技術規格

Full name:	uridine monophosphate synthetase
Synonyms:	OPRT
Swissprot:	P11172
Gene Accession:	BC000364
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

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