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  • 小鼠抗AMDHD1單克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW6222
    • 應(yīng)用 : 僅限于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:40
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中文名稱(chēng):小鼠抗AMDHD1單克隆抗體

英文名稱(chēng): Anti-AMDHD1 mouse monoclonal antibody

別      名: amidohydrolase domain containing 1; HMFT1272

相關(guān)類(lèi)別: 一抗

儲(chǔ)      存: 冷凍(-20℃)

宿      主: Mouse

抗      原: AMDHD1

反應(yīng)種屬: Human

標(biāo)  記 物: Unconjugate

克隆類(lèi)型: mouse monoclonal



技術(shù)規(guī)格

Background:

AMDHD1 (amidohydrolase domain containing 1), also known as probable imidazolonepropionase, is a 426 amino acid protein belonging to the hutI family. AMDHD1 participates in hydrolase activity, acting on carbon-nitrogen bonds, but not peptide bonds, in cyclic amides. AMDHD1 also functions in imidazolonepropionase activity and metal ion binding, whereby binding one iron or zinc ion per subunit. AMDHD1 is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes within 132 million bases and makes up approximately 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, characterized by heart and facial developmental defects, is caused by a mutant form of the PTPN11 gene product, SH-PTP2. Chromosome 12 is also linked to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster that encodes C-type lectin proteins, which mediate the NK cell response to MHC I interaction.

Applications:

WB, IHC

Name of antibody:

AMDHD1

Immunogen:

Fusion protein of human AMDHD1

Full name:

amidohydrolase domain containing 1

Synonyms:

HMFT1272

SwissProt:

Q96NU7

IHC positive control:

Human pancreas tissue

IHC Recommend dilution:

200-500

WB Predicted band size:

47 KD

WB Positive control:

Human liver tissue lysates

WB Recommended dilution:

200-1000


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