中文名稱: UBE2A 抗原(重組蛋白)
英文名稱: UBE2A Antigen (Recombinant Protein)
別 名: ubiquitin conjugating enzyme E2 A; UBC2; HHR6A; MRXSN; RAD6A; MRXS30
儲 存: 冷凍(-20℃)
相關類別:抗原
Full name: |
ubiquitin conjugating enzyme E2 A |
Synonyms: |
UBC2; HHR6A; MRXSN; RAD6A; MRXS30 |
Swissprot: |
P49459 |
Gene Accession: |
BC010175 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants. |