中文名稱: TRIM23 抗原(重組蛋白)
英文名稱: TRIM23 Antigen (Recombinant Protein)
別 名: tripartite motif containing 23; ARD1; ARFD1; RNF46
儲 存: 冷凍(-20℃)
相關類別:抗原
概 述
Full name: |
tripartite motif containing 23 |
Synonyms: |
ARD1; ARFD1; RNF46 |
Swissprot: |
P36406 |
Gene Accession: |
BC022510 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. |