中文名稱: TNNI3 抗原(重組蛋白)
英文名稱: TNNI3 Antigen (Recombinant Protein)
別 名: CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF
相關類別:抗原
儲 存: 冷凍(-20℃)
概 述
技術規格
Full name: |
troponin I type 3 (cardiac) |
Synonyms: |
CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF |
Swissprot: |
P19429 |
Gene Accession: |
BC096165 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). |