中文名稱: TMPRSS2 抗原(重組蛋白)
英文名稱: TMPRSS2 Antigen (Recombinant Protein)
別 名: transmembrane protease, serine 2; PP9284; PRSS10
儲 存: 冷凍(-20℃)
相關類別:抗原
概 述
技術規格
Full name: |
transmembrane protease, serine 2 |
Synonyms: |
PP9284; PRSS10 |
Swissprot: |
O15393 |
Gene Accession: |
BC051839 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. |