中文名稱:兔抗CDC45多克隆抗體
英文名稱: Anti-CDC45 rabbit polyclonal antibody
別 名: cell division cycle 45; CDC45L; CDC45L2; PORC-PI-1
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: CDC45
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants. |
Applications: |
ELISA, IHC |
Name of antibody: |
CDC45 |
Immunogen: |
Fusion protein of human CDC45 |
Full name: |
cell division cycle 45 |
Synonyms: |
CDC45L; CDC45L2; PORC-PI-1 |
SwissProt: |
O75419 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human colorectal cancer |
IHC Recommend dilution: |
25-100 |