中文名稱: RIOX2 抗原(重組蛋白)
別 名: ribosomal oxygenase 2; ROX; MDIG; MINA; NO52; JMJD10; MINA53
儲 存: 冷凍(-20℃)
相關類別:抗原
概 述
技術規格
Full name: |
ribosomal oxygenase 2 |
Synonyms: |
ROX; MDIG; MINA; NO52; JMJD10; MINA53 |
Swissprot: |
Q8IUF8 |
Gene Accession: |
BC014928 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. |