中文名稱:兔抗CBL (phospho-Tyr700)多克隆抗體
別 名: CBL2; NSLL; C-CBL; RNF55; FRA11B
相關類別: 一抗
儲 存: 冷凍(-20℃) 避光
宿 主: Rabbit
抗 原: CBL (phospho-Tyr700)
反應種屬: Human, Mouse, Rat
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術規格
Background: |
Participates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including PDGFA, EGF and CSF1, and terminates signaling. |
Applications: |
WB, IHC, IF |
Name of antibody: |
CBL (phospho-Tyr700) |
Immunogen: |
Synthetic peptide of human CBL (phospho-Tyr700) |
Full name: |
Cbl proto-oncogene, E3 ubiquitin protein ligase (phospho-Tyr700) |
Synonyms: |
CBL2; NSLL; C-CBL; RNF55; FRA11B |
SwissProt: |
P22681 |
IHC positive control: |
Human breast carcinoma |
IHC Recommend dilution: |
50-100 |
WB Predicted band size: |
120 kDa |
WB Positive control: |
HT29 cells treated with UV |
WB Recommended dilution: |
500-1000 |
IF Positive control: |
Hela cells |
IF Recommended dilution |
100-200 |