中文名稱:兔抗CAV1多克隆抗體
英文名稱: Anti-CAV1 rabbit polyclonal antibody
別 名: CGL3; PPH3; BSCL3; VIP21; MSTP085
相關(guān)類別: 一抗
儲(chǔ) 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: CAV1
反應(yīng)種屬: Human, Mouse, Rat
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1. |
Applications: |
ELISA, WB |
Name of antibody: |
CAV1 |
Immunogen: |
Synthetic peptide of human CAV1 |
Full name: |
caveolin 1, caveolae protein, 22kDa |
Synonyms: |
CGL3; PPH3; BSCL3; VIP21; MSTP085 |
SwissProt: |
Q03135 |
ELISA Recommended dilution: |
2000-5000 |
WB Predicted band size: |
20 kDa |
WB Positive control: |
Human leiomyosarcoma tissue |
WB Recommended dilution: |
500-2000 |