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中文名稱：兔抗CAPN10多克隆抗體
英文名稱： Anti-CAPN10 rabbit polyclonal antibody
別 名： CANP10; NIDDM1
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： CAPN10
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. |
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Applications: |
ELISA, WB |
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Name of antibody: |
CAPN10 |
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Immunogen: |
Synthetic peptide of human CAPN10 |
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Full name: |
calpain 10 |
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Synonyms: |
CANP10; NIDDM1 |
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SwissProt: |
Q9HC96 |
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ELISA Recommended dilution: |
5000-10000 |
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WB Predicted band size: |
75 kDa |
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WB Positive control: |
A172 and 293T cell lysates |
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WB Recommended dilution: |
200-1000 |
