中文名稱:兔抗BRAF(Phospho-Ser446)多克隆抗體
Background: |
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. |
Applications: |
WB |
Name of antibody: |
BRAF(Phospho-Ser446) |
Immunogen: |
Peptide sequence around phosphorylation site of Serine 446 (R-D-S(p)-S-D) derived from Human B-RAF. |
Full name: |
B-Raf proto-oncogene, serine/threonine kinase |
Synonyms: |
NS7; BRAF1; RAFB1; B-RAF1 |
SwissProt: |
P15056 |
WB Predicted band size: |
84 kDa |
WB Positive control: |
293 cells lysates treated with EGF |
WB Recommended dilution: |
500-1000 |