中文名稱:兔抗ARRB2多克隆抗體
Background: |
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Applications: |
ELISA, WB |
Name of antibody: |
ARRB2 |
Immunogen: |
Synthetic peptide of human ARRB2 |
Full name: |
arrestin beta 2 |
Synonyms: |
ARB2; ARR2; BARR2 |
SwissProt: |
P32121 |
ELISA Recommended dilution: |
5000-10000 |
WB Predicted band size: |
40 kDa |
WB Positive control: |
HEPG2 and Hela cell lysates |
WB Recommended dilution: |
200-1000 |