Background: |
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps16 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Two transcript variants encoding different isoforms have been found for this gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
VPS16 |
Immunogen: |
Fusion protein of human VPS16 |
Full name: |
VPS16 core subunit of CORVET and HOPS complexes |
Synonyms: |
hVPS16 |
SwissProt: |
Q9H269 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
25-100 |