Background: |
This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
VEGFB |
Immunogen: |
Synthetic peptide of human VEGFB |
Full name: |
vascular endothelial growth factor B |
Synonyms: |
VRF, VEGFL |
SwissProt: |
P49765 |
ELISA Recommended dilution: |
5000-240000 |
IHC positive control: |
Human thyroid cancer |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
21 kDa |
WB Positive control: |
Mouse brain tissue |
WB Recommended dilution: |
500-2000 |