Background: |
The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Alternate transcriptional splice variants have been characterized. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
TRAF5 |
Immunogen: |
Fusion protein of human TRAF5 |
Full name: |
TNF receptor-associated factor 5 |
Synonyms: |
RNF84; MGC:39780 |
SwissProt: |
O00463 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human lung cancer and human thyroid cancer |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
64 kDa |
WB Positive control: |
Jurkat cells |
WB Recommended dilution: |
500-2000 |