Background: |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
TNFRSF10A |
Immunogen: |
Synthetic peptide of human TNFRSF10A |
Full name: |
TNF receptor superfamily member 10a |
Synonyms: |
DR4; APO2; CD261; TRAILR1; TRAILR-1 |
SwissProt: |
O00220 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human colorectal cancer and Human liver cancer |
IHC Recommend dilution: |
25-50 |
WB Predicted band size: |
50 kDa |
WB Positive control: |
PC-3 and LOVO cell lysates |
WB Recommended dilution: |
500-2000 |