Background: |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. |
Applications: |
IHC |
Name of antibody: |
TNFRSF1A |
Immunogen: |
Synthesized peptide derived from Internal of human TNF receptor-1. |
Full name: |
tumor necrosis factor receptor superfamily, member 1A |
Synonyms: |
FPF; MS5; p55; p60; TBP1; TNF-R; TNFAR; TNFR1; p55-R; CD120a; TNFR55; TNFR60; TNF-R-I; TNF-R55; TNFR1-d2 |
SwissProt: |
P19438 |
IHC positive control: |
Human breast carcinoma tissue |
IHC Recommend dilution: |
50-100 |