Background: |
The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene. |
Applications: |
WB |
Name of antibody: |
TLK1 |
Immunogen: |
Synthesized peptide derived from internal of human TLK1. |
Full name: |
tousled-like kinase 1 |
Synonyms: |
PKU-beta |
SwissProt: |
Q9UKI8 |
WB Predicted band size: |
87 kDa |
WB Positive control: |
Rat brain tissue and NIH/3T3 cells lysates |
WB Recommended dilution: |
500-3000 |