Background: |
Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternate splicing results in multiple transcript variants of this gene. |
Applications: |
WB |
Name of antibody: |
THPO |
Immunogen: |
Fusion protein of human THPO |
Full name: |
Thrombopoietin |
Synonyms: |
ML; TPO; MGDF; MKCSF; MPLLG; THCYT1 |
SwissProt: |
P40225 |
WB Predicted band size: |
38 kDa |
WB Positive control: |
293 cells |
WB Recommended dilution: |
500-2000 |