Background: |
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. |
Applications: |
IHC |
Name of antibody: |
TGFBR2(Phospho-Ser225/250) |
Immunogen: |
Peptide sequence around phosphorylation site of Serine 225/250(D-R-S(p)-D-I) derived from Human TGF β Receptor II. |
Full name: |
transforming growth factor, beta receptor II (70/80kDa) |
Synonyms: |
AAT3; FAA3; LDS2; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TGFR-2; TGFbeta-RII |
SwissProt: |
P37173 |
IHC positive control: |
Human brain tissue |
IHC Recommend dilution: |
50-100 |