中文名稱：兔抗TGFB2多克隆抗體

英文名稱： Anti-TGFB2 rabbit polyclonal antibody

別名： LDS4; TGF-beta2

相關(guān)類別：一抗

儲(chǔ) 存： 冷凍（-20℃）

宿主： Rabbit

抗原： TGFB2

反應(yīng)種屬： Human, Mouse, Rat

標(biāo) 記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1;7)(q41;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.

Applications:

ELISA, IHC

Name of antibody:

TGFB2

Immunogen:

Synthetic peptide of human TGFB2

Full name:

transforming growth factor, beta 2

Synonyms：

LDS4; TGF-beta2

SwissProt:

P61812

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and Human lung cancer

IHC Recommend dilution:

25-100

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兔抗TGFB2多克隆抗體

Background:	This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1;7)(q41;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.
Applications:	ELISA, IHC
Name of antibody:	TGFB2
Immunogen:	Synthetic peptide of human TGFB2
Full name:	transforming growth factor, beta 2
Synonyms：	LDS4; TGF-beta2
SwissProt:	P61812
ELISA Recommended dilution:	2000-5000
IHC positive control:	Human liver cancer and Human lung cancer
IHC Recommend dilution:	25-100