Background: |
This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. |
Applications: |
ELISA, WB |
Name of antibody: |
TFAP2B |
Immunogen: |
Synthetic peptide of human TFAP2B |
Full name: |
transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
Synonyms: |
AP-2B; AP2-B |
SwissProt: |
Q92481 |
ELISA Recommended dilution: |
1000-2000 |
WB Predicted band size: |
50 kDa |
WB Positive control: |
Jurkat cells |
WB Recommended dilution: |
200-1000 |