Background: |
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. |
Applications: |
WB |
Name of antibody: |
TAF4 |
Immunogen: |
Synthesized peptide derived from internal of human TAF4. |
Full name: |
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa |
Synonyms: |
TAF2C; TAF4A; TAF2C1; TAFII130; TAFII135 |
SwissProt: |
O00268 |
WB Predicted band size: |
110 kDa |
WB Positive control: |
NIH/3T3 cells lysate |
WB Recommended dilution: |
500-3000 |