Background: |
The protein encoded by this gene is an intermediate filament (IF) family member. IF proteins are cytoskeletal proteins that confer resistance to mechanical stress and are encoded by a dispersed multigene family. This protein has been found to form a linkage between desmin, which is a subunit of the IF network, and the extracellular matrix, and provides an important structural support in muscle. Two alternatively spliced variants encoding different isoforms have been described for this gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
SYNM |
Immunogen: |
Synthetic peptide corresponding to a region derived from 1516-1528 amino acids of human SYNM |
Full name: |
synemin |
Synonyms: |
DMN; SYN |
SwissProt: |
O15061 |
ELISA Recommended dilution: |
5000-10000 |
IHC Positive control: |
Human liver cancer; |
IHC Recommended dilution: |
20-100 |