Background: |
Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. Does not have ubiquitin-specific peptidase activity, but could be a competitor of ubiquitin C-terminal hydrolases (UCHs). |
Applications: |
ELISA, IHC |
Name of antibody: |
USP39 |
Immunogen: |
Fusion protein of human USP39 |
Full name: |
ubiquitin specific peptidase 39 |
Synonyms: |
65K; SAD1; CGI-21; HSPC332; SNRNP65 |
SwissProt: |
Q53GS9 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human colorectal cancer and Human lung cancer |
IHC Recommend dilution: |
25-100 |