Background: |
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
STX1A |
Immunogen: |
Synthetic peptide of human STX1A |
Full name: |
Syntaxin 1A (brain) |
Synonyms: |
STX1; HPC-1; P35-1; SYN1A |
SwissProt: |
Q16623 |
ELISA Recommended dilution: |
2000-10000 |
IHC positive control: |
Human ovarian cancer |
IHC Recommend dilution: |
50-200 |
WB Predicted band size: |
33 kDa |
WB Positive control: |
Mouse brain tissue |
WB Recommended dilution: |
1000-5000 |