Background: |
This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI). Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
STS |
Immunogen: |
Synthetic peptide of human STS |
Full name: |
steroid sulfatase (microsomal), isozyme S |
Synonyms: |
ES; ASC; XLI; ARSC; SSDD; ARSC1 |
SwissProt: |
P08842 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
10-50 |
WB Predicted band size: |
65 kDa |
WB Positive control: |
Hela cell lysate |
WB Recommended dilution: |
200-1000 |