Background: |
This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. |
Applications: |
WB |
Name of antibody: |
STK11(Phospho-Ser428) |
Immunogen: |
Peptide sequence around phosphorylation site of serine428 (R-L-S(p)-A-C) derived from Human LKB1 . |
Full name: |
serine/threonine kinase 11 |
Synonyms: |
PJS; LKB1; hLKB1 |
SwissProt: |
Q15831 |
WB Predicted band size: |
49 kDa |
WB Positive control: |
Hela cells lysates treated with PMA |
WB Recommended dilution: |
500-1000 |