Background: |
Sterile-20 (Ste20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cyto-solic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to Ste20 are divided into two groups, the PAK subfamily and the GCK subfamily. The mammalian Ste20-like kinases (MST kinases), also known as Krs proteins, are members of the GCK subfamily. Ksr-1 (MST-2) and Ksr-2 (MST-1) are both direct substrates of caspase-3 that accelerate caspase-3 activation. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
STK3/STK4 |
Immunogen: |
Synthetic peptide of human STK3/STK4 |
Full name: |
serine threonine kinase 3/4 |
Synonyms: |
KRS1; MST2/KRS2; MST1; YSK3; TIIAC |
SwissProt: |
Q13043 |
ELISA Recommended dilution: |
2000-10000 |
IHC positive control: |
Human Lymphoma and Human liver cancer |
IHC Recommend dilution: |
100-300 |
WB Predicted band size: |
56 kDa |
WB Positive control: |
PC3 and hela cells, human bladder carcinoma tissue and A172 cells, hepG2 cells |
WB Recommended dilution: |
500-2000 |