Background: |
Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe3+ to Fe2+. Can also reduce of Cu2+ to Cu1+, suggesting that it participates in copper homeostasis. Uses NADP+ as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP. |
Applications: |
WB, IF |
Name of antibody: |
STEAP3 |
Immunogen: |
Synthesized peptide derived from internal of human STEA3. |
Full name: |
STEAP family member 3, metalloreductase |
Synonyms: |
STMP3; TSAP6; AHMIO2; dudlin-2 |
SwissProt: |
Q658P3 |
WB Predicted band size: |
55 kDa |
WB Positive control: |
COLO205 cells lysate |
WB Recommended dilution: |
500-3000 |
IF positive control: |
Hela cells |
IF Recommend dilution: |
100-500 |